KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE1
All Species:
7.27
Human Site:
T510
Identified Species:
17.78
UniProt:
Q8IWY4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWY4
NP_766638.2
988
107910
T510
S
Q
A
R
A
K
E
T
A
R
Q
P
L
L
D
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
P514
E
G
L
R
P
A
L
P
E
K
H
S
S
V
K
Rhesus Macaque
Macaca mulatta
XP_001108689
995
108761
L514
E
T
A
R
Q
P
L
L
G
P
R
G
P
A
N
Dog
Lupus familis
XP_538874
1009
111038
G528
A
S
R
I
L
G
Q
G
G
A
P
C
S
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZL8
1018
111587
T540
S
Q
E
R
A
K
D
T
L
R
H
P
L
L
D
Rat
Rattus norvegicus
O88281
1574
165428
T820
V
G
S
R
C
Q
D
T
C
S
A
G
W
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
P449
E
G
L
R
Q
K
T
P
E
K
H
N
S
V
K
Chicken
Gallus gallus
O73775
704
78120
P275
E
T
G
T
H
N
C
P
P
D
F
I
C
Q
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
R531
K
T
A
L
S
D
K
R
A
T
E
N
V
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782645
907
100435
T447
A
G
S
G
S
L
I
T
A
Y
V
E
I
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.3
89.5
64.8
N.A.
89.2
22.4
N.A.
55.9
21.2
N.A.
64.6
N.A.
N.A.
N.A.
N.A.
43.3
Protein Similarity:
100
76.6
91.6
76.9
N.A.
92.6
31.8
N.A.
67.9
32.7
N.A.
77.2
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
6.6
13.3
0
N.A.
73.3
13.3
N.A.
13.3
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
26.6
13.3
N.A.
80
33.3
N.A.
26.6
6.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
30
0
20
10
0
0
30
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
10
0
10
0
0
10
10
0
10
% C
% Asp:
0
0
0
0
0
10
20
0
0
10
0
0
0
10
20
% D
% Glu:
40
0
10
0
0
0
10
0
20
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
40
10
10
0
10
0
10
20
0
0
20
0
0
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
30
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
0
0
0
10
10
0
10
% I
% Lys:
10
0
0
0
0
30
10
0
0
20
0
0
0
0
20
% K
% Leu:
0
0
20
10
10
10
20
10
10
0
0
0
20
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
20
0
0
20
% N
% Pro:
0
0
0
0
10
10
0
30
10
10
10
20
10
0
0
% P
% Gln:
0
20
0
0
20
10
10
0
0
0
10
0
0
20
0
% Q
% Arg:
0
0
10
60
0
0
0
10
0
20
10
0
0
0
0
% R
% Ser:
20
10
20
0
20
0
0
0
0
10
0
10
30
0
0
% S
% Thr:
0
30
0
10
0
0
10
40
0
10
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
10
0
10
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _